License
International Journal of Paediatric Orthopaedics is licensed under a
https://creativecommons.org/licenses/by-nc-sa/4.0/
Publisher
Official Journal of:
Paediatric Orthopaedic Society of India (POSI)
Publisher:
ResearchOne Publishing House,
An "Indian Orthopaedic Research Group (IORG) initiative.
IORG House,
A-203, Manthan Apts, Shreesh CHS, Hajuri Road,
Thane [West], Maharashtra, India.
Pin Code- 400604
Tel- 02225834545
Publisher Email: indian.ortho@gmail.com
Editor Email: editor.ijpo@gmail.com
pwktoto
boom138
hk lotto
sibayak99
triadtoto
triadtoto
triad4d
boom138
triad4d
triadtoto
triad4d
spin338
holyslot123
Amanah99
Rupiah777
horastogel
cuanslot
okta138
tango168
lotus777
bostoto138
medali69
milojitu
Lotre78
lux77
Gorilatoto
Hoki338
Dewapoker77
baikbet
sule78
lavatoto
uang138
Merak99
porto4d
hemattoto
Kaca138
puri138
anginbet
Joglo4d
juragantogel
Mahyong69
sojubet
sakti777
StarJoker69
grab78
spacetogel
jarum169
Kudatoto
pangkalanbet
ten88
opera99
satelit69
koin88
pondok338
jaring338
pubtogel
milo338
thor388
deltatoto
bdjitu
mirana99
amat123
autobet123
Shio77
gemoy188
planet888
Maria99
makmurwin
pakdejp
geber777
lato777
Melatibet
bankslot
hujantogel
coco69
Rusa69
Apollo303
sule777
namabet
Mars77
moon138
Pancingslot
Pulaubet
rumah88
cumi303
prada68
versace138
Koala4d
lobby69
lux78
usaha4d
kambingtogel
Musangtoto
delta777
Jeweltoto
pos188
lava77
maluku303
kompor88
luckslot
Lotre169
lotus68
raffi169
tambang388
ratuzeusqq
dinasti99
Modalhoki108
asiajitu
judi78
astra78
partaiqq
rumah69
Meriam123
evosbet88
Sayangbet
Lilin4d
Cemaraslot
furla69
kumis4d
Bandungslot
japan78
hokislot123
hulk303
Pragmatic69
chivas69
krisna188
Lyonslot
ASIABET168
topislot
bola123
ultra365
ios55
kompor77
sinaga138
kelapabet
padang777
Rajawin777
Jakarta88slot
Becak168
babetogel
primaslot
Moonslot
palu338
pulautogel
botaktogel
platinum138
cici169
gunturtogel
Kacang4d
dewabet138
spin388
homebet69
bursatoto
mami4d
pasbet
aduhoki
lava69
pagoda388
meledak99
dalang138
Gama188
dino777
papua338
darat123
hokiwin55
Cobra777
Merak88
crown78
preman77
grab188
terminal388
apiwin
madura78
sinar303
Dupawin
Santuy188
kera388
Modalhoki68
omuslot
Peri123
divabet
macau388
Angsa138
keris69
DOMINOPKV
Bos69
Sawitjitu
jaring99
layar77
tayototo
taro168
pejuang388
next88
harapan168
hemat123
Shio88
apidewa77
parisjp
pohon69
Lotre777
taruna123
asean168
giga69
StarJoker123
tempat99
Sisir4d
Tokek78
bosstogel
pakdeslot88
wisslot
rumah108
dominoslot
cola123
jili88
kompas77
bisnis77
kungfu69
Arjuna77
sensa123
Piramida4d
gacor365
pucuk777
Lotre123
wayang777
Gama178
WLA88
langitmpo
Robot4d
kumbang123
Logam4d
Sawit138
Bca168
petir88
tokyobet
tempo123
Permen178
Gacorbos99
wiratogel
LUNAS805
sateslot
barbar188
maxwin123
pecahtogel
Menang77
demotogel
trisula4d
candy138
bostoto188
demo388
citatogel
SIRKUIT138
Boy4d
Kalaslot
formulabet
Kode99
icon55
domino123
cartel303
jingga4d
Luxuryqq
space168
Legenda4d
porto169
api69
ASIAMPO77
wiki69
fasslot
cincin77
rajatoto68
Merak78
batastogel
gem108
buku99
furlabet
versace168
Sayang777
marvel365
kumis138
sushitoto
cbototo
latar77
Hadiah4d
solusi138
udara4d
sayang188
maha777
milo55
taro303
Dunia88
sejuta188
Dewapokertogel
Luxurygg
KOBOYPOKER
Aksara77
amat303
unggul123
oris77
kingdomjitu
merci4d
Aontoto
gemoyslot
geloratoto
layar69
winning138
sobet78
klik303
gilagg
bantamtoto
Sbo4d
Tombol4d
maya303
spin6d
sumo123
lambe88
barbar88
kadobet168
solid169
oasis365
karo303
duta69
sumo88
Pandawa123
ipar777
bengkelslot
macanslot
abc69
judolbetqq
Laku123
obor77
Lampion4d
memori77
jepang169
plntoto
ASIAPKV
Duyung88
Hijau123
dewanslot
MAXWIN888
SUARABET77
empirebet
Kucingtoto
kakek138
idr188
coca123
sisri77
jamu123
cumi99
fire123
persentogel
moon4d
dutabet
jaring365
Bigwin178
Gacorbos169
toto388
evosgamingg
kado99
WLA55
kadal303
rumah168
Poker138
Aztectoto
gasing78
extrabet
urban168
Topengslot
planet388
Angkatoto77
mulia88
qq69
luck388
epictogel
GACORBOS
icon169
atlas169
bentototo
jamu4d
libas169
holiday69
hulk77
skor77
karo168
colekbet
Bendera99
suhu4d
Dayak123
radentogel
KOBOY888
memori108
lajubet888
JUARAWIN88
BIMO77
jokerbetqq
AREASLOTO
juara77
dewi138
DEWIBET777
nusapoker
jilibet
Ikan303
kadalslot
depototo
harum123
pawang88
krisna123
madu55
Khusustogel
taktik388
Wahana4d
ovo168
mesinslot
Gogo90
bromo99
Badutjitu
Mega777
sentosa69
kamus168
Tigerslot
tempatslot
wazebet
sekai777
airtogel
Agen99
colek777
pasang388
pigi388
Angkatoto123
batam69
kudetabet69
mewah123
fuji338
papua78
murahpoker
cincin365
memori69
hantu78
anak777
Kapten99
Nanas188
Glory77
wiki78
PEDANGBET
mahjongs138
ipar78
motoslot88
POV99
bingo4d
ratuslot777
YUPI188
ASIASLOT888
fire777
pasti138
batam777
julietslot
iklan88
kamus77
sobet99
capital99
Sicbo4d
paris4d
daya365
amat168
roslot55
Kaktusslot
cakra123
Abu123
krisna77
guntur365
PEDANGJITU
panca123
Kodok123
ASIAKING777
JPSLOT168
wuling88
kaya77
KOBOIBOLA
garpu777
kingbet169
pir69
extra188
oren77
cair365
kingdomjp
dewaslot138
nagapoker777
cici138
Daun777
surga6d
holyslottoto
jakarta303
dinasti777
suara78
Mbah4d
HOKIOM88
zona77
unggul169
tempat123
Arus138
retro388
mampirtoto
sulaptogel
nagawin168
pecah188
bangsa338
ASIAHOKI88
neopoker
mesin188
canduslot777
dino78
asus88
Mangga4d
kumistogel
nama88
kkslot55
LUNA999
Tokcer69
Logam303
kkslot108
lgo188
gemoy777
ultra99
tahunslot
ligajp88
kampusslot
babe69
macau128
taktik123
kado338
Angsa77
latarslot
juliet777
lavaslot
suburbet
doyan77
ladang77
Dupaslot
YUPIBET
AREA188
betagg
usaha169
AREAWIN88
megawinbet
Tokcer168
mandiri99
MANTAP138
mahal99
Gobertogel
abc77
mulia99
bonus303
kembar388
sensatogel
atom188
gebyar77
baik388
balon138
Master77
ovo338
gaco169
edanbet
pistolslot
air169
kembang169
dna303
wigo123
ladangslot
pasang338
suryatogel
DOMINOBET77
kembar188
diva388
pohonjitu
Sakuraqq
kumis168
ASIATOTO777
Premium188
rupiah4d
CERIAPOKER
KAYA78
kebunbet
sawi69
pub365
pesiar69
Wild777
Tores777
paus168
bom108
Dollarjitu
vegas77
wis338
Kancil69
angkasaslot
Dolan138
semangat303
jaritogel
daun69
nova123
darat303
SERUBET88
selat123
hantu88
serbatoto
balon123
tenbet
padi78
benuawin
Sensa188
Emas88
Rajawalitogel
musangtogel
sarana78
sugar365
lexus108
bom123
kso123
luck4d
puncak88
vista123
muara69
Rutantoto
ceria88
RAFI777
alasbet
durentoto
mpomaster
cipitbet
usaha138
leobet
mantra168
Akun188
Nanastogel
alexa88
Tombol168
slotbom68
solid78
gunturslot
sake138
Gloryslot
luck77
raksasa138
mildbet
Doku123
Yakuza777
bostoto77
jutawan168
odin123
lampu168
cumi168
mega169
puri188
petatogel
dadu168
mahadewa168
karirtogel
istana88
serbu123
kumbang99
pulau169
Sarangslot88
muliaslot
tiktoktoto
retro4d
ayo68
Dugem88
jepe338
bns99
leo303
turbo77
timur77
baiktogel
masterbet123
Mansionslot
petirslot
retro69
unggul168
POV69
musik168
kapaljudi777
Habanero138
marvel188
kejubet
ios99
Ninjaslot
permen169
fix338
koi138
madura168
gerbang338
desa77
sushi168
Ikanslot
opera123
oren365
luckbet
Rusa77
Ungu77
hugo99
medan123
zodiaktoto
papua168
mansion88
luck99
asean188
rajazeus138
seru78
kampung99
Target99
gas123
coca4d
dinastibet
sultanbet188
Alamtoto
pwktoto pwktoto
pwktoto
nagatoto
boom138
rajagaming-51
rajagaming-52
rajagaming-53
rajagaming-54
rajagaming-55
rajagaming-56
rajagaming-57
rajagaming-58
rajagaming-59
rajagaming-6
rajagaming-60
rajagaming-61
rajagaming-62
rajagaming-63
rajagaming-64
rajagaming-65
rajagaming-66
rajagaming-67
rajagaming-68
rajagaming-69
rajagaming-7
rajagaming-70
rajagaming-71
rajagaming-72
rajagaming-73
rajagaming-74
rajagaming-75
rajagaming-76
rajagaming-77
rajagaming-78
rajagaming-79
rajagaming-8
rajagaming-80
rajagaming-81
rajagaming-82
rajagaming-83
rajagaming-84
rajagaming-85
rajagaming-86
rajagaming-87
rajagaming-88
rajagaming-89
rajagaming-9
rajagaming-90
rajagaming-91
rajagaming-92
rajagaming-93
rajagaming-94
rajagaming-95
rajagaming-96
rajagaming-97
rajagaming-98
rajagaming-99
sibayak99
nagatoto88
triad4d
triadmacau
pwktoto
boom138
sibayak99
vinaslot
triadtotogroup
nagatoto88
garwa4d
Kirintoto
triadsgp
triadsyd
triadjitu
triadmacau
triadtoto
triadtogel
triad4d
triadhk
torpedo99
scatter99
boom138
bosslot138
sibayak99
emas69
triad303
triadslot
pwktoto
pwktoto
garwa4d
agamslot
agam138
nagatoto88
dewihoky
kudatoto
scatter99
emas69
superwinslot
lidoslot
lido123
lido69
kawal69
tvjp
triadhk
HK LOTTO
iconbet
jpspin88
jpspin303
mikrostar88
sontoto
suka777
triadtogel
torpedo4d
daget169
HK LOTTO
pwktoto
pwktoto
bentengslot
bentengtoto
benteng99
bintangjp88
kretektogel
bantengslot
gwktoto
waktoto
vinaslot
vinaslot
pwk777
triadhk
triadmacau
triadjitu
triadhk
garwa4d
torpedo4d
nagatoto88
sibayak99
triad4d
triadtogel
triad4d
torpedo4d
boom138
emas69
scatter99
pwktoto
boom138
pwktoto
nagatoto88
nagatoto88
boom138
triad4d
triadtogel
triadjitu
boom138
triadtoto
triadtogel
triadhk
nagatoto88
garwa4d
torpedo4d
triadmacau
triadtoto
triadmacau
triadtoto
triadtogel
triadhk
scatter99
sibayak99
emas69
triadjitu
emas69
scatter99
sibayak99
boom138
pwktoto
torpedo4d
torpedo4d
torpedo4d
torpedo4d
nagatoto88
nagatoto88
nagatoto88
garwa4d
garwa4d
garwa4d
triadtoto
triadtoto
triadtoto
triadtogel
triadtogel
triadtogel
triad4d
triad4d
triad4d
triad4d
triad4d
triad4d
triadhk
triadhk
triadhk
triadhk
triadhk
triadhk
triadmacau
triadmacau
triadjitu
triadjitu
triadjitu
scatter99
scatter99
scatter99
scatter99
scatter99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
boom138
emas69
emas69
rokettoto
rokettoto
rokettoto
rokettoto
bukitdita
kirintoto
kirintoto
triadsgp
triadsgp
triadsyd
triadsyd
torpedo99
torpedo99
torpedo99
torpedo99
premium138
premium138
premium138
premium138
premium138
premium138
bosslot138
bosslot138
bosslot
bosslot138
bosslot138
pusat69
pusat69
dompet69
dompet69
dompet69
dompet138
dompet188
dompet168
dompet123
harta69
triadslot
triadslot
triad303
138vip
138vip
triadtogel
triadtoto
triad4d
triadhk
pancawin
badaitoto
triadtoto
vinaslot
torpedo4d
pwktoto boom138
pwktoto
pwktoto
triadtoto
triadhk
triad4d
triadtogel
triadjitu
triadmacau
boom138
garwa4d
scatter99
emas69
torpedo4d
nagatoto88
vinaslot
vinaslot
vinaslot
pwktoto
bejo99
langit188
pwktoto
boom138
hk lotto
sibayak99
triadtoto
triadtoto
triad4d
boom138
triad4d
triadtoto
triad4d
spin338
holyslot123
Amanah99
Rupiah777
horastogel
cuanslot
okta138
tango168
lotus777
bostoto138
medali69
milojitu
Lotre78
lux77
Gorilatoto
Hoki338
Dewapoker77
baikbet
sule78
lavatoto
uang138
Merak99
porto4d
hemattoto
Kaca138
puri138
anginbet
Joglo4d
juragantogel
Mahyong69
sojubet
sakti777
StarJoker69
grab78
spacetogel
jarum169
Kudatoto
pangkalanbet
ten88
opera99
satelit69
koin88
pondok338
jaring338
pubtogel
milo338
thor388
deltatoto
bdjitu
mirana99
amat123
autobet123
Shio77
gemoy188
planet888
Maria99
makmurwin
pakdejp
geber777
lato777
Melatibet
bankslot
hujantogel
coco69
Rusa69
Apollo303
sule777
namabet
Mars77
moon138
Pancingslot
Pulaubet
rumah88
cumi303
prada68
versace138
Koala4d
lobby69
lux78
usaha4d
kambingtogel
Musangtoto
delta777
Jeweltoto
pos188
lava77
maluku303
kompor88
luckslot
Lotre169
lotus68
raffi169
tambang388
ratuzeusqq
dinasti99
Modalhoki108
asiajitu
judi78
astra78
partaiqq
rumah69
Meriam123
evosbet88
Sayangbet
Lilin4d
Cemaraslot
furla69
kumis4d
Bandungslot
japan78
hokislot123
hulk303
Pragmatic69
chivas69
krisna188
Lyonslot
ASIABET168
topislot
bola123
ultra365
ios55
kompor77
sinaga138
kelapabet
padang777
Rajawin777
Jakarta88slot
Becak168
babetogel
primaslot
Moonslot
palu338
pulautogel
botaktogel
platinum138
cici169
gunturtogel
Kacang4d
dewabet138
spin388
homebet69
bursatoto
mami4d
pasbet
aduhoki
lava69
pagoda388
meledak99
dalang138
Gama188
dino777
papua338
darat123
hokiwin55
Cobra777
Merak88
crown78
preman77
grab188
terminal388
apiwin
madura78
sinar303
Dupawin
Santuy188
kera388
Modalhoki68
omuslot
Peri123
divabet
macau388
Angsa138
keris69
DOMINOPKV
Bos69
Sawitjitu
jaring99
layar77
tayototo
taro168
pejuang388
next88
harapan168
hemat123
Shio88
apidewa77
parisjp
pohon69
Lotre777
taruna123
asean168
giga69
StarJoker123
tempat99
Sisir4d
Tokek78
bosstogel
pakdeslot88
wisslot
rumah108
dominoslot
cola123
jili88
kompas77
bisnis77
kungfu69
Arjuna77
sensa123
Piramida4d
gacor365
pucuk777
Lotre123
wayang777
Gama178
WLA88
langitmpo
Robot4d
kumbang123
Logam4d
Sawit138
Bca168
petir88
tokyobet
tempo123
Permen178
Gacorbos99
wiratogel
LUNAS805
sateslot
barbar188
maxwin123
pecahtogel
Menang77
demotogel
trisula4d
candy138
bostoto188
demo388
citatogel
SIRKUIT138
Boy4d
Kalaslot
formulabet
Kode99
icon55
domino123
cartel303
jingga4d
Luxuryqq
space168
Legenda4d
porto169
api69
ASIAMPO77
wiki69
fasslot
cincin77
rajatoto68
Merak78
batastogel
gem108
buku99
furlabet
versace168
Sayang777
marvel365
kumis138
sushitoto
cbototo
latar77
Hadiah4d
solusi138
udara4d
sayang188
maha777
milo55
taro303
Dunia88
sejuta188
Dewapokertogel
Luxurygg
KOBOYPOKER
Aksara77
amat303
unggul123
oris77
kingdomjitu
merci4d
Aontoto
gemoyslot
geloratoto
layar69
winning138
sobet78
klik303
gilagg
bantamtoto
Sbo4d
Tombol4d
maya303
spin6d
sumo123
lambe88
barbar88
kadobet168
solid169
oasis365
karo303
duta69
sumo88
Pandawa123
ipar777
bengkelslot
macanslot
abc69
judolbetqq
Laku123
obor77
Lampion4d
memori77
jepang169
plntoto
ASIAPKV
Duyung88
Hijau123
dewanslot
MAXWIN888
SUARABET77
empirebet
Kucingtoto
kakek138
idr188
coca123
sisri77
jamu123
cumi99
fire123
persentogel
moon4d
dutabet
jaring365
Bigwin178
Gacorbos169
toto388
evosgamingg
kado99
WLA55
kadal303
rumah168
Poker138
Aztectoto
gasing78
extrabet
urban168
Topengslot
planet388
Angkatoto77
mulia88
qq69
luck388
epictogel
GACORBOS
icon169
atlas169
bentototo
jamu4d
libas169
holiday69
hulk77
skor77
karo168
colekbet
Bendera99
suhu4d
Dayak123
radentogel
KOBOY888
memori108
lajubet888
JUARAWIN88
BIMO77
jokerbetqq
AREASLOTO
juara77
dewi138
DEWIBET777
nusapoker
jilibet
Ikan303
kadalslot
depototo
harum123
pawang88
krisna123
madu55
Khusustogel
taktik388
Wahana4d
ovo168
mesinslot
Gogo90
bromo99
Badutjitu
Mega777
sentosa69
kamus168
Tigerslot
tempatslot
wazebet
sekai777
airtogel
Agen99
colek777
pasang388
pigi388
Angkatoto123
batam69
kudetabet69
mewah123
fuji338
papua78
murahpoker
cincin365
memori69
hantu78
anak777
Kapten99
Nanas188
Glory77
wiki78
PEDANGBET
mahjongs138
ipar78
motoslot88
POV99
bingo4d
ratuslot777
YUPI188
ASIASLOT888
fire777
pasti138
batam777
julietslot
iklan88
kamus77
sobet99
capital99
Sicbo4d
paris4d
daya365
amat168
roslot55
Kaktusslot
cakra123
Abu123
krisna77
guntur365
PEDANGJITU
panca123
Kodok123
ASIAKING777
JPSLOT168
wuling88
kaya77
KOBOIBOLA
garpu777
kingbet169
pir69
extra188
oren77
cair365
kingdomjp
dewaslot138
nagapoker777
cici138
Daun777
surga6d
holyslottoto
jakarta303
dinasti777
suara78
Mbah4d
HOKIOM88
zona77
unggul169
tempat123
Arus138
retro388
mampirtoto
sulaptogel
nagawin168
pecah188
bangsa338
ASIAHOKI88
neopoker
mesin188
canduslot777
dino78
asus88
Mangga4d
kumistogel
nama88
kkslot55
LUNA999
Tokcer69
Logam303
kkslot108
lgo188
gemoy777
ultra99
tahunslot
ligajp88
kampusslot
babe69
macau128
taktik123
kado338
Angsa77
latarslot
juliet777
lavaslot
suburbet
doyan77
ladang77
Dupaslot
YUPIBET
AREA188
betagg
usaha169
AREAWIN88
megawinbet
Tokcer168
mandiri99
MANTAP138
mahal99
Gobertogel
abc77
mulia99
bonus303
kembar388
sensatogel
atom188
gebyar77
baik388
balon138
Master77
ovo338
gaco169
edanbet
pistolslot
air169
kembang169
dna303
wigo123
ladangslot
pasang338
suryatogel
DOMINOBET77
kembar188
diva388
pohonjitu
Sakuraqq
kumis168
ASIATOTO777
Premium188
rupiah4d
CERIAPOKER
KAYA78
kebunbet
sawi69
pub365
pesiar69
Wild777
Tores777
paus168
bom108
Dollarjitu
vegas77
wis338
Kancil69
angkasaslot
Dolan138
semangat303
jaritogel
daun69
nova123
darat303
SERUBET88
selat123
hantu88
serbatoto
balon123
tenbet
padi78
benuawin
Sensa188
Emas88
Rajawalitogel
musangtogel
sarana78
sugar365
lexus108
bom123
kso123
luck4d
puncak88
vista123
muara69
Rutantoto
ceria88
RAFI777
alasbet
durentoto
mpomaster
cipitbet
usaha138
leobet
mantra168
Akun188
Nanastogel
alexa88
Tombol168
slotbom68
solid78
gunturslot
sake138
Gloryslot
luck77
raksasa138
mildbet
Doku123
Yakuza777
bostoto77
jutawan168
odin123
lampu168
cumi168
mega169
puri188
petatogel
dadu168
mahadewa168
karirtogel
istana88
serbu123
kumbang99
pulau169
Sarangslot88
muliaslot
tiktoktoto
retro4d
ayo68
Dugem88
jepe338
bns99
leo303
turbo77
timur77
baiktogel
masterbet123
Mansionslot
petirslot
retro69
unggul168
POV69
musik168
kapaljudi777
Habanero138
marvel188
kejubet
ios99
Ninjaslot
permen169
fix338
koi138
madura168
gerbang338
desa77
sushi168
Ikanslot
opera123
oren365
luckbet
Rusa77
Ungu77
hugo99
medan123
zodiaktoto
papua168
mansion88
luck99
asean188
rajazeus138
seru78
kampung99
Target99
gas123
coca4d
dinastibet
sultanbet188
Alamtoto
pwktoto pwktoto
pwktoto
nagatoto
boom138
rajagaming-51
rajagaming-52
rajagaming-53
rajagaming-54
rajagaming-55
rajagaming-56
rajagaming-57
rajagaming-58
rajagaming-59
rajagaming-6
rajagaming-60
rajagaming-61
rajagaming-62
rajagaming-63
rajagaming-64
rajagaming-65
rajagaming-66
rajagaming-67
rajagaming-68
rajagaming-69
rajagaming-7
rajagaming-70
rajagaming-71
rajagaming-72
rajagaming-73
rajagaming-74
rajagaming-75
rajagaming-76
rajagaming-77
rajagaming-78
rajagaming-79
rajagaming-8
rajagaming-80
rajagaming-81
rajagaming-82
rajagaming-83
rajagaming-84
rajagaming-85
rajagaming-86
rajagaming-87
rajagaming-88
rajagaming-89
rajagaming-9
rajagaming-90
rajagaming-91
rajagaming-92
rajagaming-93
rajagaming-94
rajagaming-95
rajagaming-96
rajagaming-97
rajagaming-98
rajagaming-99
sibayak99
nagatoto88
triad4d
triadmacau
pwktoto
boom138
sibayak99
vinaslot
triadtotogroup
nagatoto88
garwa4d
Kirintoto
triadsgp
triadsyd
triadjitu
triadmacau
triadtoto
triadtogel
triad4d
triadhk
torpedo99
scatter99
boom138
bosslot138
sibayak99
emas69
triad303
triadslot
pwktoto
pwktoto
garwa4d
agamslot
agam138
nagatoto88
dewihoky
kudatoto
scatter99
emas69
superwinslot
lidoslot
lido123
lido69
kawal69
tvjp
triadhk
HK LOTTO
iconbet
jpspin88
jpspin303
mikrostar88
sontoto
suka777
triadtogel
torpedo4d
daget169
HK LOTTO
pwktoto
pwktoto
bentengslot
bentengtoto
benteng99
bintangjp88
kretektogel
bantengslot
gwktoto
waktoto
vinaslot
vinaslot
pwk777
triadhk
triadmacau
triadjitu
triadhk
garwa4d
torpedo4d
nagatoto88
sibayak99
triad4d
triadtogel
triad4d
torpedo4d
boom138
emas69
scatter99
pwktoto
boom138
pwktoto
nagatoto88
nagatoto88
boom138
triad4d
triadtogel
triadjitu
boom138
triadtoto
triadtogel
triadhk
nagatoto88
garwa4d
torpedo4d
triadmacau
triadtoto
triadmacau
triadtoto
triadtogel
triadhk
scatter99
sibayak99
emas69
triadjitu
emas69
scatter99
sibayak99
boom138
pwktoto
torpedo4d
torpedo4d
torpedo4d
torpedo4d
nagatoto88
nagatoto88
nagatoto88
garwa4d
garwa4d
garwa4d
triadtoto
triadtoto
triadtoto
triadtogel
triadtogel
triadtogel
triad4d
triad4d
triad4d
triad4d
triad4d
triad4d
triadhk
triadhk
triadhk
triadhk
triadhk
triadhk
triadmacau
triadmacau
triadjitu
triadjitu
triadjitu
scatter99
scatter99
scatter99
scatter99
scatter99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
sibayak99
boom138
emas69
emas69
rokettoto
rokettoto
rokettoto
rokettoto
bukitdita
kirintoto
kirintoto
triadsgp
triadsgp
triadsyd
triadsyd
torpedo99
torpedo99
torpedo99
torpedo99
premium138
premium138
premium138
premium138
premium138
premium138
bosslot138
bosslot138
bosslot
bosslot138
bosslot138
pusat69
pusat69
dompet69
dompet69
dompet69
dompet138
dompet188
dompet168
dompet123
harta69
triadslot
triadslot
triad303
138vip
138vip
triadtogel
triadtoto
triad4d
triadhk
pancawin
badaitoto
triadtoto
vinaslot
torpedo4d
pwktoto boom138
pwktoto
pwktoto
triadtoto
triadhk
triad4d
triadtogel
triadjitu
triadmacau
boom138
garwa4d
scatter99
emas69
torpedo4d
nagatoto88
vinaslot
vinaslot
vinaslot
pwktoto
bejo99
langit188
pwktoto
Septic Arthritis Management: Current Guidelines
Volume 8 | Issue 1 | January-April 2022 | Page: 08-13 | Gaurav Gupta, Easwar T. Ramani, Gaurav Garg, Maulin Shah
DOI-10.13107/ijpo.2022.v08i01.128
Authors: Gaurav Gupta MS Ortho. [1, 2], Easwar T. Ramani MS Ortho. [3, 4 ], Gaurav Garg MS Ortho. [5], Maulin Shah MS Ortho. [6]
[1] Department of Paediatric Orthopaedics, Asian Hospital, Faridabad, UP, India.
[2] Department of Orthopaedics, Child Ortho Clinic, Faridabad & Delhi, India.
[3] Department of Paediatric Orthopaedics, Baby Memorial Hospital, Kozhikode, Kerala, India.
[4] Department of Paediatric Orthopaedics and Spine Surgery, Palakkad District Cooperative & Research Centre, Palakkad, Kerala, India.
[5] Department of Paediatric Orthopaedics, Excelcare Hospital, Jaipur, India.
[6] Department of Paediatric Orthopaedics, Orthokid Clinic, Ahmedabad, Gujarat, India.
Address of Correspondence
Dr. Maulin Shah,
Consultant Paediatric Orthopaedic Surgeon, Orthokid Clinic, Ahmedabad, Gujarat, India.
E-mail: maulinmshah@gmail.com
Abstract
Septic arthritis is an orthopaedic emergency that is more commonly seen in infants and young children. Release of proteolytic enzymes leads to permanent destruction of intra-articular cartilage and subchondral bone as early as 72 hours after onset. Hip and knee are the most commonly involved joints. Staphylococcus aureus is the most common causative organism across all paediatric age groups. Recently, there is a significant increase in incidence of Klebsiella and Pseudomonas, especially in neonates. Sensitivity patterns of causative organisms are also changing with increasing resistance to empirical antibiotics, requiring the use of higher antibiotics.
The detection of septic arthritis in neonates is challenging. The physician has to rely on indirect signs and maintain a high index of suspicion. C-reactive protein (CRP) along with difficulty in weight bearing have a better predictive value in diagnosis. Ultrasonography (USG) is a useful tool for quick screening of a joint and to detect effusion. Many recent studies have suggested percutaneous drainage/aspiration as an equally effective modality to manage septic joints, thus avoiding the morbidity of open arthrotomy and the risks of general anaesthesia. Lack of response to minimally invasive methods warrant an open approach. Antero-lateral arthrotomy is preferred over the posterior approach to avoid iatrogenic damage to the blood supply of the femoral head. Arthroscopic lavage of the septic joint is also becoming popular. The choice of empiric antibiotic treatment should be based on age, vaccination status and underlying co-morbidities. There is growing evidence in literature for short-course intravenous (IV) therapy. Delayed diagnosis, sickle cell disease, and infection caused by certain strains of methicillin-resistant staphylococcus aureus (MRSA) are predispose to orthopaedic sequelae.
Keywords: Septic Arthritis, Arthrotomy, Osteomyelitis.
References
1. Momodu II, Savaliya V. Septic Arthritis.In:StatPearls[Internet.Treasure Island(FL):StatPearlsPublishing;2022 https://www.ncbi.nlm.nih.gov/books/NBK538176/
2. Anil Agarwal, Aditya N. Aggarwal. Bone and Joint Infections in Children: Septic Arthritis. Indian J Pediatr 2015 July 21. DOI 10.1007/s12098-015-1816-1.
3. T. Sreenivas, A. R. Nataraj, Anand Kumar, Jagdish Menon. Neonatal septic arthritis in a tertiary care hospital: a descriptive study. Eur J Orthop Surg Traumatol 2016 May 6. DOI 10.1007/s00590-016-1776-9.
4. Gireesh Sankaran, Balaji Zacharia1, Antony Roy1, Sulaikha Puthan Purayil. Current clinical and bacteriological profile of septic arthritis in young infants: a prospective study from a tertiary referral centre. European Journal of Orthopaedic Surgery & Traumatology 2018 February 9. https://doi.org/10.1007/s00590-018-2142-x.
5. Rai A, Chakladar D, Bhowmik S, Mondal T, Nandy A, Maji B, et al. Neonatal septic arthritis: Indian perspective. Eur J Rheumatol 2020; 7(Suppl 1): S72-S77.
6. Agarwal A, Aggarwal AN. Septic arthritis in children. In: Agarwal A, Aggarwal AN, editors. Pediatric osteoarticular infections. Delhi: Jaypee; 2014. p. 60–74.
7. Giovanni Autore, Luca Bernardi, Susanna Esposito. Update on Acute Bone and Joint Infections in Paediatrics: A Narrative Review on the Most Recent Evidence-Based Recommendations and Appropriate Anti Infective Therapy. Antibiotics 2020, 9, 486; doi:10.3390/antibiotics9080486.
8. Sultan J, Hughes PJ. Septic arthritis or transient synovitis of the hip in children: the value of clinical prediction algorithms. J Bone Joint Surg Br. 2010;92(9):1289–1293.
9. Ju KL, Zurakowski D, Kocher MS. Differentiating between methicillin-resistant and methicillin-sensitive Staphylococcus aureus osteomyelitis in children: an evidence-based clinical prediction algorithm. J Bone Joint Surg Am. 2011;93(18):1693–1701
10. Yagupsky P, Dubnov-Raz G, Gené A, Ephros M, Israeli-Spanish Kin-gella kingae Research Group Differentiating Kingella kingae septic arthritis of the hip from transient synovitis in young children. J Pediatr. 2014;165(5):985–989.
11. Kocher MS, Mandiga R, Zurakowski D, Barnewolt C, Kasser JR. Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children. J Bone Joint Surg Am. 2004 Aug;86(8):1629-35. doi: 10.2106/00004623-200408000-00005. PMID: 15292409.
12. Pääkkönen M. Septic arthritis in children: diagnosis and treatment. Pediatric Health Med Ther. 2017;8:65-68. Published 2017 May 18. 10.2147/PHMT.S115429.
13. Singhal R, Perry DC, Khan FN, Cohen D, Stevenson HL, James LA, Sampath JS, Bruce CE. The use of CRP within a clinical prediction algorithm for the differentiation of septic arthritis and transient synovitis in children. J Bone Joint Surg Br. 2011 Nov;93(11):1556-61. doi: 10.1302/0301-620X.93B11.26857. PMID: 22058311.
14. Krogstad P. Osteomyelitis and septic arthritis. In: Feigin RD, Cherry JD, editors. Textbook of Pediatric Infectious Diseases. 6th ed. Philadelphia, PA: Saunders; 2009. pp. 725–748.
15. G. Fabry, E. Miere. Septic arthritis hip in children : poor results after late and inadequate treatment. JPO -A , 3: 461-466, 1983.
16. W A Herndon, S Knauer, J A Sullivan, R H Gross. Management of septic arthritis in children. J Pediatr Ortho, Sep-Oct 1986;6(5):576-8. doi: 10.1097/01241398-198609000-00009.
17. Uri Givon 1, Boaz Liberman, Amos Schindler, Alexander Blankstein, Abraham Ganel. Treatment of septic arthritis of the hip joint by repeated ultrasound-guided aspirations. J Pediatr Orthop May-Jun 2004;24(3):266-70. doi: 10.1097/00004694-200405000-00006.
18. Daniel M Weigl 1, Tali Becker, Eyal Mercado, Elhanan Bar-On. Percutaneous aspiration and irrigation technique for the treatment of pediatric septic hip: effectiveness and predictive parameters. J Pediatr Orthop B 2016 Nov;25(6):514-9. doi: 10.1097/BPB.0000000000000345.
19. Ahmad Essa 1, Michael Asa’af, Haim Shtarker. Preliminary results: continuous double luminal catheter drainage for the management of septic hip arthritis in children. J Pediatr Orthop B,2022 Jan 1;31(1):e11-e16. doi: 10.1097/BPB.0000000000000866.
20. Kristin S Livingston 1, Leslie A Kalish 2, Donald S Bae 3, Young-Jo Kim 3, Benjamin J Shore. Wash, Rinse, Repeat: Which Patients Undergo Serial Joint Irrigation in Pediatric Septic Hip Arthritis? J Pediatr Orthop. 2019 Aug;39(7):e494-e499. doi: 10.1097/BPO.0000000000001323.
21. Gaurav Gupta 1, Qaisur Rabbi, Vikas Bohra, Maulin M Shah. Protrusio acetabulae as a sequel to septic arthritis of the hip with obturator internus pyomyositis. J Pediatr Orthop B,2021 Nov 1;30(6):572-578. doi: 10.1097/BPB.0000000000000823.
22. Garg R, Ho J, Gourineni PV. Simplified arthroscopic lavage of pediatric septic hip: case series. J Pediatr Orthop B. 2020 May;29(3):304-308. doi: 10.1097/BPB.0000000000000717.
23. Thompson RM, Gourineni P. Arthroscopic Treatment of Septic Arthritis in Very Young Children. J Pediatr Orthop. 2017 Jan;37(1):e53-e57. doi: 10.1097/BPO.0000000000000659
24. Eric W Edmonds 1 2, Christina Lin 1, Christine L Farnsworth 2, James D Bomar 2, Vidyadhar V Upasani 1 2 . A Medial Portal for Hip Arthroscopy in Children With Septic Arthritis: A Safety Study. J Pediatr Orthop Nov/Dec 2018;38(10):527-531. doi: 10.1097/BPO.0000000000000861.
25. Scott Rosenfeld 1, Derek T Bernstein, Shiva Daram, John Dawson, Wei Zhang. Predicting the Presence of Adjacent Infections in Septic Arthritis in Children. J Pediatr Orthop 2016 Jan;36(1):70-4. doi: 10.1097/BPO.0000000000000389.
26. Corey O Montgomery 1, Eric Siegel, Robert D Blasier, Larry J Suva. Concurrent septic arthritis and osteomyelitis in children. J Pediatr Orthop , 2013 Jun;33(4):464-7. doi: 10.1097/BPO.0b013e318278484f.
27. Jedidiah E Schlung 1, Tracey P Bastrom 2, Joanna H Roocroft 2, Peter O Newton 2, Scott J Mubarak 1 2, Vidyadhar V Upasani. Femoral Neck Aspiration Aids in the Diagnosis of Osteomyelitis In Children With Septic Hip. J Pediatr Orthop ,Nov/Dec 2018;38(10):532-536. doi: 10.1097/BPO.0000000000000868.
28.Clinical Practice Guideline by PIDS and IDSA • JPIDS 2021
29. Ohl CA. Infectious arthritis of native joints. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone; 2010:1443-1456.
30. Liu C, Bayer A, Cosgrove SE, et al; Infectious Diseases Society of America. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis. 2011;52(3):e18–e55
31. No authors listed. British Society for Antimicrobial Chemotherapy.http://www.bsac.org.uk/pyxis/Bone%20and%20joint/Septic%20arthritis/Septic%20arthritis.htm(date last accessed 28 February 2009).
32. Vinod MB, Matussek J, Curtis N, Graham HK, Carapetis JR. Duration of antibiotics in children with osteomyelitis and septic arthritis. J Paediatr Child Health 2002;38:363-7
33. Peltola H, Paakkonen M, Kallio P, Kallio MJ; OM-SA Study Group. Clindamycin vs. first-generation cephalosporins for acute osteoarticular infections of childhood – a prospective quasi-randomized controlled trial. Clin Microbiol Infect. 2012;18(6):582–589.
34. Peltola H, Paakkonen M, Kallio P, Kallio MJ; Osteomyelitis-Septic Arthritis (OM-SA) Study Group. Prospective, randomized trial of 10 days versus 30 days of antimicrobial treatment, including a short-term course of parenteral therapy, for childhood septic arthritis. Clin Infect Dis. 2009;48(9):1201–1210
(Article Text HTML) (Full Text PDF)
Pelvic Pyomyositis in Children: Current Concepts Review
Volume 8 | Issue 1 | January-April 2022 | Page: 02-07 | Archan Desai, Ashish Ranade, Mohan V. Belthur, Sandeep Patwardhan, Gauri A. Oka
DOI-10.13107/ijpo.2022.v08i01.127
Authors: Archan Desai [1], Ashish Ranade [1, 2], Mohan V. Belthur [3], Sandeep Patwardhan [4], Gauri A. Oka [1]
[1] Department of Orthopaedics, Bharati Hospital and Research Centre, Pune, Maharashtra, India.
[2] Department of Orthopaedics, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
[3] Department of Child Health & Orthopaedics, University of Arizona College of Medicine-Phoenix, USA.
[4] Department of Orthopaedics, Sancheti Hospital, Pune, Maharashtra, India.
Address of Correspondence
Dr. Ashish Ranade,
Consultant Paediatric Orthopaedic Surgeon, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India. Visiting Pediatric Orthopaedic Surgeon, Bharati Vidyapeeth Medical College Hospital, Pune, Maharashtra, India
E-mail: ranadea2@gmail.com
Abstract
Pyomyositis in children is an uncommon bacterial infection of skeletal muscles which has more frequently been described in tropical areas, but it is becoming increasingly recognized in temperate climates too. Any muscle group in the body can be involved, but it commonly affects the large muscle groups which are located around the pelvic girdle and lower extremities. Clinical presentation is very similar to septic arthritis of the hip and needs to be diagnosed early. MRI is the investigation of choice. Depending on the severity this condition, it can be treated conservatively with antibiotics in its early stage and with percutaneous or formal incision and drainage in later stages. Generally, if it is diagnosed early, good outcomes can be expected.
Keywords: Pelvic Pyomyositis, Septic arthritis, Infection, Magnetic resonance imaging
References
1. Bickels J, Ben-Sira L, Kessler A, Wientroub S. Primary pyomyositis. J Bone Joint Surg Am. 2002; 84(12):2277-2286.
2. Anand SV, Evans KT. Pyomyositis. Br J Surg. 1964; 51:917-920.
3. Levin MJ, Gardner P, Waldvogel FA. An un-usual infection due to staphylococcus aureus. N Engl J Med. 1971; 284(4):196-198.
4. Ciampi MA, Sadigh M, Sherwood JA, Protopapas Z, Thornton GF, Andriole VT. Temperate pyomyositis at two community hos-pitals. Infect Dis Clin Pract. 1998; 7:265-273.
5. Chiedozi LC: Pyomyositis: review of 205 cases in 112 patients, Am J Surg 137:255, 1979
6. De Boeck H, Noppen L, Desprechins B: Pyomyositis of the adductor muscles mimicking an infection of the hip. Diagnosis by magnetic resonance imaging: a case report, J Bone Joint Surg Am 76:747, 1994.
7. Hernandez RJ, Strouse PJ, Craig CL, et al: Focal pyomyositis of the perisciatic muscles in children, AJR Am J Roentgenol 179:1267, 2002.
8. Kadambari D, Jagdish S: Primary pyogenic psoas abscess in children, Pediatr Surg Int 16:408, 2000.
9. Orlicek SL, Abramson JS, Woods CR, et al: Obturator internus muscle abscess in children, J Pediatr Orthop 21:744, 2001.
10. Garcia-Mata S, Hidalgo-Ovejero A, Esparza-Estaun J. Primaryobturator-muscle pyomyositis in immunocompetent children. JChild Orthop. 2012;6:205–15.
11. Taksande A, Vilhekar K, Gupta S. Primary pyomyositis in a child. Int J Infect Dis. 2009;13(4):e149–51.
12. Christin L, Sarosi GA. Pyomyositis in North America: case reports and review. Clin Infect Dis. 1992;15:668–77.
13. Crum NF (2004) Bacterial pyomyositis in the United States. Am JMed 117(6):420–428
14. Moriarty P, Leung C, Walsh M, Nourse C (2015) Increasingpyomyositis presentations among children in Queensland,Australia. Pediatr Infect Dis J 34(1):1–4
15. Brown JD, Wheeler B (1984) Pyomyositis. Report of 18 cases inHawaii. Arch Intern Med 144(9):1749–1751
16. Verma S, Singhi SC, Marwaha RK, et al. Tropical pyomyositis inchildren: 10 years experience of a tertiary care hospital in northernIndia. J Trop Pediatr. 2013;59(3):243–5.
17. Gambhir IS, Singh DS, Gupta SS, Gupta PR, Kumar M. Tropicalpyomyositis in India: a clinico-histopathological study. J Trop MedHyg. 1992;95(1):42–6.
18. Malhotra P, Singh S, Sud A, et al. Tropical pyomyositis-experienceof a tertiary care hospital in North West India. J Assoc PhysiciansIndia. 2000;48:1057–60.
19. Chauhan S, Kumar R, Singh KK, Chauhan SS. Tropical pyomyositis: adiagnostic dilemma. J Ind Acad Clin Med. 2004;5:52–4.
20. Chauhan S, Jain S, Varma S, Chauhan SS. Tropical pyomyositis(myositis tropicans): current prospective. Postgrad Med J. 2004;80:267–70.
21. Smith MI, Vickers AB. Natural history of 338 treated and untreatedpatients with staphylococcal septicaemia (1936–1955). Lancet.1960;1(7138):1318–22.
22. Jayoussi R, Bialik V, Eyal A, Shehadeh N, Etzioni A. Pyomyositiscaused by vigorous exercise in a boy. Acta Paediatr. 1995;84(2):226–7.
23. Singh SB, Singh VP, Gupta S, Gupta RM, Sunder S. Tropical myo-sitis: a clinical, immunological and histopathological study. J AssocPhysicians India. 1989;37(9):561–3
24. Flier S, Dolgin SE, Saphir RL, et al: A case confirming the progressive stages of pyomyositis, J Pediatr Surg 38:1551, 2003.
25. .Moriarty, Leung C, Walsh M, Nourse C. Increasing pyomyositis presenting among children in Queensland, Australia. PediatrInfect Dis J. 2015;34(1):1–4.
26. Pannaraj PS, Hulten KG, Gonzalez BE, Mason Jr EO, Kaplan SL.Infective pyomyositis and myositis in children in the era of com-munity-acquired, methicillin-resistant Staphylococcus aureus infec-tion. Clin Infect Dis. 2006;43:953–60.
27. Mitchell PD, Hunt DM, Lyall H, Nolam M, et al. Panton-Valentineleukocidin-secreting Staphylococcus aureus causing sever muscu-loskeletal sepsis in children. A new threat. J Bone Joint Surg (Br).2007;89:1239–42.
28. Menge TJ, Cole HA, Mignemi ME, et al. Medial approach fordrainage of the obturator musculature in children.J Pediatr Orthop.2014;34:307–315.
29. Spiegel DA, Meyer JS, Dormans JP, et al. Pyomyositis in childrenand adolescents: report of 12 cases and review of the literature.JPediatr Orthop. 1999;19:143–150.
30. Renwick SE, Ritterbusch JF. Pyomyositis in children.J PediatrOrthop. 1993;13:769–772.
31. Mazur JM, Ross G, Cummings J, et al. Usefulness of magneticresonance imaging for the diagnosis of acute musculoskeletalinfections in children.J Pediatr Orthop. 1995;15:144–147.
32. Peckett WR, Butler-Manuel A, Apthorp LA. Pyomyositis of theiliacus muscle in a child.J Bone Joint Surg Br. 2001;83:103–105.
33. Thomas S, Tytherleigh-Strong G, Dodds R. Pyomyositis of theiliacus muscle in a child.J Bone Joint Surg Br. 2001;83:619–620.
34. Yuh WT, Schreiber AE, Montgomery WJ, et al. Magnetic resonanceimaging of pyomyositis.Skeletal Radiol. 1988;17:190–193.
35. Kocher MS, Zurakowski D, Kasser JR (1999) Differentiating be-tween septic arthritis and transient synovitis of the hip in children:an evidence- based clinical prediction algorithm. J Bone Joint SurgAm 81(12):1662–1670
36. Bertrand SL, Lincoln ED, Prohaska MG. Primary pyomyositis ofthe pelvis in children: a retrospective review of 8 cases.Orthopedics. 2011;34(12):832–40.
37. Unnikrishnan PN, Perry DC, George H, Bassi R, Bruce CE.Tropical primary pyomyositis in children of the UK: an emerging medical challenge. Int Orthop. 2010;34:109–13.
38. Kiran M, Mohamed S, Newton A, George H, Garg N, Bruce C. Pelvic pyomyositis in children: changing trends in occurrence and management. Int Orthop. 2018 May;42(5):1143-1147.
39. Birkbeck D, Watson JT (1995) Obturator internus pyomyositis. Acase report. Clin Orthop Relat Res 316:221–226
40. Tucker RE, Winter WG, Del Valle C, Uematsu A, Libke R(1978) Pyomyositis mimicking malignant tumor. Three casereports. J Bone Joint Surg Am 60:701–703
41. Karmazyn B, Loder RT, Kleiman MB, et al. The role of pelvicmagnetic resonance in evaluating nonhip sources of infection inchildren with acute nontraumatic hip pain.J Pediatr Orthop.2007;27:158–164.
42. Ovadia D, Ezra E, Ben-Sira L, et al. Primary pyomyositis inchildren: a retrospective analysis of 11 cases.J Pediatr Orthop B.2007;16:153–159.
43. Browne LP, Mason EO, Kaplan SL, et al. Optimal imaging strategyfor community-acquiredStaphylococcus aureusmusculoskeletalinfections in children.Pediatr Radiol. 2008;38:841–847.
44. Karmazyn B, Kleiman MB, Buckwalter K, et al. Acute pyomyositisof the pelvis: the spectrum of clinical presentations and MRfindings.Pediatr Radiol. 2006;36:338–343.
45. Marin C, Sanchez-Alegre ML, Gallego C, et al. Magnetic resonanceimaging of osteoarticular infections in children.Curr Probl DiagnRadiol. 2004;33:43–59.
46. Theodorou SJ, Theodorou DJ, Resnick D. MR imaging findings ofpyogenic bacterial myositis (pyomyositis) in patients with localmuscle trauma: illustrative cases.Emerg Radiol. 2007;14:89–96.
47. Damski GB, Garin EH, Ballinger WE, et al. Generalized non-suppurative myositis with staphylococcal septicemia. J Pediatr.1980;96:694–7.
48. Ameh EA (1999) Pyomyositis in children: analysis of 31 cases.Ann Trop Paediatr 19:263–265
49. Vij N, Ranade AS, Kang P, Belthur MV. Primary Bacterial Pyomyositis in Children: A Systematic Review. J Pediatr Orthop. 2021 Oct 1;41(9):e849-e854.
50. Song J, Letts M, Monson R (2001) Differentiation of psoasmuscle abscess from septic arthritis of the hip in children. ClinOrthop Relat Res 391:258–265
51. Armstrong DG, D’Amato CR, Strong ML (1993) Three cases ofstaphylococcal pyomyositis in adolescence, including one patientwith neurologic compromise. J Pediatr Orthop 13:452–455
52. Teague DC, Graney DO, Routt ML Jr. Retropubic vascular hazardsof the ilioinguinal exposure: a cadaveric and clinical study.J OrthopTrauma. 1996;10:156–159.
53. Karakurt L, Karaca I, Yilmaz E, et al. Corona mortis: incidence andlocation.Arch Orthop Trauma Surg. 2002;122:163–164.
54. Luhmann SJ, Jones A, Schootman M, et al. Differentiation betweenseptic arthritis and transient synovitis of the hip in children withclinical prediction algorithms.J Bone Joint Surg Am. 2004;86-A:956–962.
55. Chauhan S, Jain S, Varma S, Chauhan SS. Tropical pyomyositis (myositis tropicans): current perspective. Postgrad Med J. 2004 May;80(943):267-70.
56. White S, Stopka S, Nimityongskul P, Jorgensen D. Transgluteal Approach for Drainage of Obturator Internus Abscess in Pediatric Patients. J Pediatr Orthop. 2017 Jan;37(1):e62-e66.
57. Hall RL, Callaghan JJ, Moloney E, Martinez S, Harrelson JM(1990) Pyomyositis in a temperate climate. Presentation, diag-nosis, and treatment. J Bone Joint Surg Am 72:1240–1244
58. Mignemi ME, Menge TJ, Cole HA, Mencio GA, Martus JE, Lovejoy S, Stutz CM, Schoenecker JG. Epidemiology, diagnosis, and treatment of pericapsular pyomyositis of the hip in children. J Pediatr Orthop. 2014 Apr-May;34(3):316-25.
59. Gupta G, Rabbi Q, Bohra V, Shah MM. Protrusio acetabulae as a sequel to septic arthritis of the hip with obturator internus pyomyositis. J Pediatr Orthop B. 2021 Nov 1;30(6):572-578.
(Article Text HTML) (Full Text PDF)
Bruck Syndrome (Bone Fragility with Congenital Joint Contractures): A Case Report
Volume 7 | Issue 3 | September-December 2021 | Page: 29-34 | Gaurav Gupta, Qaisur Rabbi, Maulin Shah, Vikas Bohra
DOI-10.13107/ijpo.2021.v07i03.120
Authors: Deepika A. Pinto MS DNB Orth. [1], Sandeep V. Vaidya MS DNB Orth. [1]
[1] Department of Paediatric Orthopaedics, Pinnacle Ortho Center, LBS Road, Thane West, Maharashtra, India.
Address of Correspondence
Dr. Deepika A. Pinto,
Clinical Associate in Paediatric Orthopaedics, Pinnacle Ortho Center, LBS Road, Thane West, Maharashtra, India.
E-mail: deepupinto@gmail.com
Abstract
Background: Bruck syndrome is a disorder in which features of osteogenesis imperfecta and arthrogryposis multiplex congenita coexist. It is an extremely rare condition with less than 40 cases reported worldwide.
Case presentation: We describe the case of a girl child, born of a consanguineous marriage, who, at birth, was noted to have flexion contractures of both knees and elbows as well as right clubfoot. Post-natally, she developed repetitive fractures of both femurs occurring with trivial trauma. She presented to us at the age 8.5 years, with short stature and inability to stand due to the severe knee flexion contractures. She also had flexion contractures at bilateral elbows. Intelligence and fine motor skills were normal. Sclerae, teeth and hearing were also normal. Radiographs revealed osteoporosis, severely deformed femora and vertebral body flattening. A diagnosis of Bruck syndrome was made on the basis of clinical findings. Genetic testing was offered, but declined by the child’s parents. She has since undergone osteotomies and rodding for both femurs, and bilateral distal femoral anterior hemi-epiphysiodesis for gradual correction of knee contractures. She is on cyclical pamidronate therapy to address bone fragility.
Conclusion: In this report, we describe the diagnostic features and management of this rare syndrome, and provide a summary of the existing literature on the disorder.
Keywords: Bruck syndrome, Osteogenesis imperfecta, Arthrogryposis, Congenital joint contractures, Bone fragility
References
1. Orpha.net. Bruck Syndrome. https://www.orpha.net/consor/cgibin/OC_Exp.php?lng=en&Expert=2771 Accessed 24th July 2020.
2. Sharma NL, Anand JS. Osteogenesis Imperfecta with Arthrogryposis Multiplex Congenita. J Indian Med Assoc. 1964;43:124–6.
3. Datta V, Sinha A, Saili A, Nangia S. Bruck syndrome. Indian J Pediatr. 2005;72(5):441–2.
4. Viljoen D, Versfeld G, Beighton P. Osteogenesis imperfecta with congenital joint contractures (Bruck Syndrome). Clin Genet. 1989;36(2):122–6.
5. Ha-Vinh R, Alanay Y, Bank RA, Campos-Xavier AB, Zankl A, Superti-Furga A, et al. Phenotypic and molecular characterization of Bruck syndrome (osteogenesis imperfecta with contractures of the large joints) caused by a recessive mutation in PLOD2. Am J Med Genet Part A. 2004;131A(2):115–20.
6. van der Slot AJ, Zuurmond A-M, Bardoel AFJ, Wijmenga C, Pruijs HEH, Sillence DO, et al. Identification of PLOD2 as Telopeptide Lysyl Hydroxylase, an Important Enzyme in Fibrosis. J Biol Chem. 2003;278(42):40967–72.
7. Shaheen R, Al-Owain M, Faqeih E, Al-Hashmi N, Awaji A, Al-Zayed Z, et al. Mutations in FKBP10 cause both Bruck syndrome and isolated osteogenesis imperfecta in humans. Am J Med Genet Part A. 2011;155(6):1448–52.
8. Bank RA, Robins SP, Wijmenga C, Breslau-Siderius LJ, Bardoel AFJ, Van der Sluijs HA, et al. Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: Indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17. Proc Natl Acad Sci. 1999;96(3):1054–8.
9. Mokete L, Robertson A, Viljoen D, Beighton P. Bruck syndrome: congenital joint contractures with bone fragility. J Orthop Sci. 2005;10(6):641–6.
10. Breslau-Siderius EJ, Engelbert RHB, Pals G, van der Sluijs JA. Bruck syndrome: a rare combination of bone fragility and multiple congenital joint contractures. J Pediatr Orthop B. 1998;7(1):35–8.
11. Moravej H, Karamifar H, Karamizadeh Z, Amirhakimi G, Atashi S, Nasirabadi S. Bruck syndrome – a rare syndrome of bone fragility and joint contracture and novel homozygous FKBP10 mutation. Endokrynol Pol. 2015;66(2):170–4.
12. Luce L, Casale M, Waldron S. A Rare Case of Bruck Syndrome Type 2 in Siblings With Broad Phenotypic Variability. Ochsner J. 2020;20(2):204–8.
13. Puig-Hervás MT, Temtamy S, Aglan M, Valencia M, Martínez-Glez V, Ballesta-Martínez MJ, et al. Mutations in PLOD2 cause autosomal-recessive connective tissue disorders within the Bruck syndrome-Osteogenesis imperfecta phenotypic spectrum. Hum Mutat. 2012;33(10):1444–9.
14. Boyce AM, Gafni RI. Approach to the Child with Fractures. J Clin Endocrinol Metab. 2011;96(7):1943–52.
15. Alman B, Goldberg MJ. Syndromes of Orthopaedic Importance. In: Lowell and Winter’s Pediatric Orthopaedics. 7th ed. Lippincott Williams & Wilkins; 2014. p. 266.
16. Otaify GA, Aglan MS, Ibrahim MM, Elnashar M, El Banna RAS, Temtamy SA. Zoledronic acid in children with osteogenesis imperfecta and Bruck syndrome: a 2-year prospective observational study. Osteoporos Int. 2016;27(1):81–92.
17. Santana A, Oleas-Santillán G, Franzone JM, Nichols LR, Bowen JR, Kruse RW. Orthopedic Manifestations of Bruck Syndrome: A Case Series with Intermediate to Long-term Follow-Up. Case Rep Orthop. 2019;2019:8014038.
(Article Text HTML) (Full Text PDF)
Introducing and Treating a Pediatric Monteggia Intermediate-Type 3 and 4 Fracture: A Case Report
Volume 7 | Issue 3 | September-December 2021 | Page: 50-52 | Pavan Soni, Tushar Agrawal
DOI-10.13107/ijpo.2021.v07i03.125
Authors: Pavan Soni D Ortho. [1], Tushar Agrawal DNB Ortho. [1]
[1] Department of Orthopaedic, Aastha Hospital, Kandivali (W), Mumbai, Maharashtra, India.
Address of Correspondence
Dr Pavan Soni
Department of Orthopaedics, Aastha Hospital, Kandivali (W), Mumbai, Maharashtra, India.
E-mail: pavan.soni22@gmail.com
Abstract
Bado based his classification of Monteggia fractures on the direction of the radial head dislocation. We present a case of a Monteggia fracture that is an intermediary between Bado type 3 and 4 occurring in a 4-year-old Indian girl. It is a fracture of the proximal ulna and radial shaft, along with a lateral dislocation of the radial head that was treated with retrograde elastic nailing of the radius fist, then the ulna. Our case report is unique because this fracture pattern has not been presented earlier in literature. Interestingly, what presented as a both bone forearm fracture, on careful examination, was a Monteggia fracture. Our report aims to help other surgeons identify and treat this complex injury, in addition, increase awareness of this rare Monteggia variant.
Keywords: Monteggia, Paediatric forearm fractures, Elbow injuries
References
[1] Olney BW, Menelaus MB. Monteggia and equivalent lesions in childhood. Journal of pediatric orthopedics. 1989 Mar 1;9(2):219-23.
[2] Bado JL. 7 The Monteggia Lesion. Clinical Orthopaedics and Related Research (1976-2007). 1967 Jan 1;50:71-86.
[3] Ravessoud FA. Lateral condylar fracture and ipsilateral ulnar shaft fracture: Monteggia equivalent lesions?. Journal of pediatric orthopedics. 1985 May 1;5(3):364-6.
[4] Arazi M, Ögün TC, Kapicioglu MS. The Monteggia lesion and ipsilateral supracondylar humerus and distal radius fractures. Journal of orthopaedic trauma. 1999 Jan 1;13(1):60-3.
[5] Bhandari N, Jindal P. Monteggia lesion in a child: Variant of a Bado Type-IV lesion. A case report. JBJS. 1996 Aug 1;78(8):1252
[6] Rang, M., Pring, M. E., & Wenger, D. R. (2005). Rang’s children’s fractures.
[7] Gleeson AP, Beattie TF. Monteggia fracture-dislocation in children. Emergency Medicine Journal. 1994 Sep 1;11(3):192-4.
(Article Text HTML) (Full Text PDF)
Temporary Transphyseal Medial Malleolar Screw Hemiepiphysiodesis for Acquired Ankle Valgus Following Fibular Graft Harvest in Children: A Series of 15 Patients
Volume 7 | Issue 3 | September-December 2021 | Page: 17-22 | Ankit Jain, Anil Agarwal, Nitish Bikram Deo, Ankur, Jatin Raj Sareen
DOI-10.13107/ijpo.2021.v07i03.117
Authors: Ankit Jain D. Ortho. [1], Anil Agarwal MS Ortho. [1], Nitish Bikram Deo MS Ortho. [1], Ankur MS Ortho. [1], Jatin Raj Sareen MS Ortho. [1]
[1] Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Delhi, India.
Address of Correspondence
Dr Anil Agarwal
Specialist, Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Delhi, India.
E-mail: anilrachna@gmail.com
Abstract
Purpose: To assess the role of temporary transphyseal medial malleolar screw hemiepiphysiodesis in cases of acquired ankle valgus following non-vascularized fibular harvest.
Methods: This retrospective chart review included 15 children (18 ankles). Exclusion criteria were inadequate records or additional procedures besides screw hemiepiphysiodesis. Radiological evaluations included lateral distal tibial angle (LDTA) and fibular station (Malhotra grade).
Results : The average patient age was 8.6 years at surgery. The overall duration of treatment was 18.2 months and post removal follow-up (5 ankles) was 16.6 months. The average correction rate was 0.48 degrees/ month. LDTA changed significantly following hemiepiphysiodesis (Pre-op 077.3 degrees/ in situ follow-up 85.9 degrees). The Malhotra grade did not change significantly during the same period. The average recurrence rate [noted in 4/5 patients] was 0.52 degrees per month. However, LDTA and Malhotra grade did not change significantly post removal.
Conclusions : We report the results of temporary transphyseal medial malleolar screw hemiepiphysiodesis for post fibular harvest acquired ankle valgus in children. Temporary hemiepiphysiodesis is a viable option for the correction of acquired ankle valgus in children. The fibular station is however not restored following the procedure. Recurrence of deformity following screw removal remains a worrying complication in some patients.
Keywords: Hemiepiphysiodesis, Ankle valgus, Growth modulation, Fibula, Harvest
References
1. Davids JR, Valadie AL, Ferguson RL, Bray EW 3rd, Allen BL Jr. Surgical management of ankle valgus in children: use of a transphyseal medial malleolar screw. J Pediatr Orthop. 1997;17:3-8.
2. Stevens PM, Belle RM. Screw epiphysiodesis for ankle valgus. J Pediatr Orthop. 1997;17:9-12.
3. Stevens PM, Kennedy JM, Hung M. Guided growth for ankle valgus. J Pediatr Orthop. 2011;31:878-83.
4. Aurégan JC, Finidori G, Cadilhac C, Pannier S, Padovani JP, Glorion C. Children ankle valgus deformity treatment using a transphyseal medial malleolar screw. Orthop Traumatol Surg Res. 2011;97:406-9.
5. Driscoll M, Linton J, Sullivan E, Scott A. Correction and recurrence of ankle valgus in skeletally immature patients with multiple hereditary exostoses. Foot Ankle Int. 2013;34:1267-73.
6. Driscoll MD, Linton J, Sullivan E, Scott A. Medial malleolar screw versus tension-band plate hemiepiphysiodesis for ankle valgus in the skeletally immature. J Pediatr Orthop. 2014;34:441-6.
7. Bayhan IA, Yildirim T, Beng K, Ozcan C, Bursali A. Medial malleolar screw hemiepiphysiodesis for ankle valgus in children with spina bifida. Acta Orthop Belg. 2014;80:414-8.
8. Chang FM, Ma J, Pan Z, Hoversten L, Novais EN. Rate of correction and recurrence of ankle valgus in children using a transphyseal medial malleolar screw. J Pediatr Orthop. 2015;35:589-92.
9. Rupprecht M, Spiro AS, Rueger JM, Stücker R. Temporary screw epiphyseodesis of the distal tibia: a therapeutic option for ankle valgus in patients with hereditary multiple exostosis. J Pediatr Orthop. 2011;31:89-94.
10. Rupprecht M, Spiro AS, Breyer S, Vettorazzi E, Ridderbusch K, Stücker R. Growth modulation with a medial malleolar screw for ankle valgus deformity. 79 children with 125 affected ankles followed until correction or physeal closure. Acta Orthop. 2015;86:611-5.
11. Rupprecht M, Spiro AS, Schlickewei C, Breyer S, Ridderbusch K, Stücker R. Rebound of ankle valgus deformity in patients with hereditary multiple exostosis. J Pediatr Orthop. 2015;35:94-9.
12. Westberry DE, Carpenter AM, Thomas JT, Graham GD, Pichiotino E, Hyer LC. Guided growth for ankle valgus deformity: the challenges of hardware removal. J Pediatr Orthop. 2020;40:e883-e888.
13. Gaukel S, Leu S, Skovguard SR, Aufdenblatten C, Ramseier LE, Vuille-Dit-Bille RN. Temporary screw epiphysiodesis for ankle valgus in children. Acta Orthop Belg. 2020;86:e supplement 37-43.
14. Steinlechner CW, Mkandawire NC. Non-vascularised fibular transfer in the management of defects of long bones after sequestrectomy in children. J Bone Joint Surg Br. 2005;87:1259-63.
15. Agarwal A, Kumar D, Agrawal N, Gupta N. Ankle valgus following non-vascularized fibular grafts in children-an outcome evaluation minimum two years after fibular harvest. Int Orthop. 2017;41:949-955.
16. Agarwal A. The regeneration at non vascularized fibular harvest site and development of ankle valgus in donor leg-investigations done over two time points. J Clin Orthop Trauma. 2019;10:999-1003.
17. Agarwal A. Fibular donor site following non vascularized harvest: clinico-radiological outcome at minimal five year follow-up. Int Orthop. 2019;43:1927-31.
18. Goh JCH, Mech AMI, Lee EH, et al. Biomechanical study on the load-bearing characteristics of the fibula and the effects of the fibular resection. Clin Orthop 1992;279:223-8.
19. González-Herranz P, del Río A, Burgos J, López-Mondejar JA, Rapariz JM. Valgus deformity after fibular resection in children. J Pediatr Orthop. 2003;23:55-9.
20. Babhulkar SS, Pande KC, Babhulkar S. Ankle instability after fibular resection. J Bone Joint Surg Br. 1995:77:258-61.
21. Kang SH, Rhee SK, Song SW, Chung JW, Kim YC, Suhl KH. Ankle deformity secondary to acquired fibular segmental defect in children. Clin Orthop Surg. 2010;2:179-85.
22. Van der Veen FJ, Strackee SD, Besselaar PP. Progressive valgus deformity of the donor-site ankle after extraperiosteal harvesting the fibular shaft in children. Treatment with osteotomy and synostosis at one session. J Orthop. 2014;12 (Suppl 1):S94-S100.
23. Lesiak AC, Esposito PW. Progressive valgus angulation of the ankle secondary to loss of fibular congruity treated with medial tibial hemiepiphysiodesis and fibular reconstruction. Am J Orthop (Belle Mead NJ). 2014;43:280-3.
24. Iamaguchi RB, Fucs PM, da Costa AC, Chakkour I. Vascularised fibular graft for the treatment of congenital pseudarthrosis of the tibia: long-term complications in the donor leg. Int Orthop. 2011;35:1065-70.
25. Fragnière B, Wicart P, Mascard E, Dudousset J (2003) Prevention of ankle valgus after vascularized fibular grafts in children. Clin Orthop Relat Res. 2003;408:245-51.
26. Sulaiman AR, Wan Z, Awang S, Che Ahmad A, Halim AS, Ahmad Mohd Zain R. Long-term effect on foot and ankle donor site following vascularized fibular graft resection in children. J Pediatr Orthop B. 2015;24:450-5.
27. Malhotra D, Puri R, Owen R. Valgus deformity of the ankle in children with spina bifida aperta. J Bone Joint Surg Br. 1984;66:381-5.
28. Gilbert A, Brockman R. Congenital pseudarthrosis of the tibia. Long-term followup of 29 cases treated by microvascular bone transfer. Clin Orthop Relat Res. 1995;314:37-44.
29. Frick SL, Shoemaker S, Mubarak SJ. Altered fibular growth patterns after tibiofibular synostosis in children. J Bone Joint Surg Am. 2001;83:247-54.
(Article Text HTML) (Full Text PDF)
Osteoid Osteoma; A Diagnostic Protocol and Treatment with Computed Tomography Guided Radio Frequency Ablation in a Series of 36 Patients.
Volume 7 | Issue 3 | September-December 2021 | Page: 13-16 | Sandeep Patwardhan, Arkesh Madegowda, Ashok Shyam, Parag Sancheti
DOI-10.13107/ijpo.2021.v07i03.116
Authors: Sandeep Patwardhan MS Ortho. [1], Arkesh Madegowda MS Ortho. [1], Ashok Shyam MS Ortho. [1, 2], Parag Sancheti MS Ortho. [1]
[1] Department of Paediatric Orthopaedics, Sancheti Institute for Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
[2] Department of Research, Indian Orthopaedic Research Group, Thane (W), Maharashtra, India.
Address of Correspondence
Dr Arkesh Madegowda
Department of Paediatric Orthopaedics, Sancheti Institute for Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
E-mail: dr.arkesh@gmail.com
Abstract
Background and purpose: Osteoid osteoma (OO) constitutes 10-12% of all benign bone tumours making it one of the most commonly occurring bone tumour. Radiofrequency ablation (RFA) offers a minimally invasive day care treatment option where in the tumour cells in the nidus are thermo-coagulated. The purpose of this study is to highlight the diagnostic protocol of OO and evaluate the safety and efficacy of RFA in its treatment.
Methods: A total of 36 patients (26 male, 10 female patients; mean age 10.33 years; age range 4-20 years) who underwent Computerized tomography (CT) guided RFA treatment for osteoid osteoma of various anatomical locations were included in this study. Patients underwent radiography and CT evaluation for diagnosis. When classical symptoms were absent and CT was inconclusive, patients underwent further evaluation with magnetic resonance imaging (MR) and nuclear scan. Features suggestive of OO in any two of these investigations was considered confirmatory and such patients were offered RFA. Patients were assessed for abolition of pain after treatment and complications if any were recorded.
Results: The intra nidus location of probe which was considered as technical success was noted in all patients. There was significant improvement in pain after RFA. Visual Analogue Scale (VAS) score improved from 7.2 preoperatively to 0.6 and 0.0 at 3 months and 6 months respectively. Two patients of tibia OO had superficial skin burns that healed within 2 weeks. One patient sustained tibia fracture at RFA site after a fall and but was pain free after 20 weeks. At the latest follow up of 28 months (range 14-56 months), there were no recurrences.
Conclusion: Diagnosis of osteoid osteoma may be challenging at times and additional investigations like MRI/nuclear bone scan along with radiography and CT aid in making an appropriate diagnosis. CT guided radiofrequency ablation of osteoid osteoma is a safe, effective and minimally invasive treatment modality with low complication rates.
Keywords: Osteoid osteoma, Computed tomography guided, Radiofrequency ablation, Minimally invasive, Day care.
References
1. Iyer RS, Chapman T, Chew FS. Pediatric bone imaging: diagnostic imaging of osteoid osteoma. AJR. 2012;198(5):1039e1052.
2. D. C.Dahlin andK. K. Unni, Bone Tumours: General Aspects and Data on 8542 Cases, Springfield: III:Thomas, 4th edition, 1987.
3. Widmann G., Schullian P., Fasser M., Niederwanger C., & Bale R. (2013). CT-guided stereotactic targeting accuracy of osteoid osteoma. The International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS, 9(3), 274-279.
4. Atesok KI, Alman BA, Schemitsch EH, Peyser A, Mankin H. Osteoid osteoma and osteoblastoma. J Am Acad Orthop Surg. 2011 Nov;19(11):678-89.
5. Carneiro BC, Da Cruz IAN, Ormond Filho AG, Silva IP, Guimarães JB, Silva FD, Nico MAC, Stump XMGRG. Osteoid osteoma: the great mimicker. Insights Imaging. 2021 Mar 8;12(1):32.
6. Cantwell C. P., Obyrne J., & Eustace S. (2004). Current trends in treatment of osteoid osteoma with an emphasis on radiofrequency ablation. European Radiology, 14(4), 607-617.
7. De Filippo M, Russo U, Papapietro VR, Ceccarelli F, Pogliacomi F, Vaienti E, Piccolo C, Capasso R, Sica A, Cioce F, Carbone M, Bruno F, Masciocchi C, Miele V. Radiofrequency ablation of osteoid osteoma. Acta Biomed. 2018 Jan 19;89(1-S):175-185.
8. Muneeb A, Solbiati L, Brace CL, et al. Image-guided tumour ablation: standardization of terminology and reporting criteria – a 10-year update. Radiology.2014;273(1):241e260.
9. Mankin HJ: Osteoid osteoma and osteoblastoma: Two related bone tumours, in Great Educator Series: Pathophysiology of Orthopaedic Diseases. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2009, vol 2, pp 79-85.
10. Rosenthal DI, Hornicek FJ, Wolfe MW, Jennings LC, Gebhardt MC, Mankin HJ: Percutaneous radiofrequency coagulation of osteoid osteoma compared with operative treatment. J Bone Joint Surg Am 1998;80(6):815-821.
11. Rosenthal DI, Hornicek FJ, Wolfe MW, Jennings LC, Gebhardt MC, Mankin HJ: Decreasing length of hospital stay in treatment of osteoid osteoma. Clin Orthop Relat Res 1999;(361):186-191.
12. Rosenthal DI, Hornicek FJ, Torriani M, Gebhardt MC, Mankin HJ: Osteoid osteoma: Percutaneous treatment with radiofrequency energy. Radiology 2003; 229(1):171-175.
13. Nijland H, Gerbers JG, Bulstra SK, Overbosch J, Stevens M, Jutte PC. Evaluation of accuracy and precision of CT-guidance in Radiofrequency Ablation for osteoid osteoma in 86 patients. PLoS One. 2017 Apr 6;12(4):e0169171.
14. Peyser A, Applbaum Y, Simanovsky N, Safran O, Lamdan R: CT-guided radiofrequency ablation of pediatric osteoid osteoma utilizing a water-cooled tip. Ann Surg Oncol 2009;16(10):2856- 2861.
15. Sahin C, Oc Y, Ediz N, Altınay M, Bayrak AH. The safety and the efficacy of computed tomography guided percutaneous radiofrequency ablation of osteoid osteoma. Acta Orthop Traumatol Turc. 2019 Sep;53(5):360-365.
16. Oc Y, Kilinc BE, Cennet S, Boyacioglu MM, Ertugrul R, Varol A. Complications of Computer Tomography Assisted Radiofrequency Ablation in the Treatment of Osteoid Osteoma. Biomed Res Int. 2019 May 15;2019:4376851.
17. Ankory R, Kadar A, Netzer D, Schermann H, Gortzak Y, Dadia S, Kollander Y, Segal O. 3D imaging and stealth navigation instead of CT guidance for radiofrequency ablation of osteoid osteomas: a series of 52 patients. BMC Musculoskelet Disord. 2019 Dec 1;20(1):579.
18. Scipione R, Anzidei M, Bazzocchi A, Gagliardo C, Catalano C, Napoli A. HIFU for bone metastases and other musculoskeletal applications. Semin Intervent Radiol. 2018;35(4):261e267.
19. Kishore S, Kothary N, Lugren M, Mohler D, Avedian R, Ghanouni P. Treatment of osteoid osteoma using MR guided high intensity focussed ultrasound: preliminary results after four patients. J Vasc Interv Radiol.
20. Yarmolenko PS, Eranki A, Partanen A, et al. Technical aspects of osteoid osteoma ablation in children using MR-guided high intensity focussed ultrasound. Int J Hyperthermia. 2018;34(1):49e58.
(Article Text HTML) (Full Text PDF)